Ubiquitin-mediated proteostasis group

The Samant Lab, at The Babraham Institute, explores the fundamental biology underlying misfolded protein ubiquitylation and clearance in health, ageing, and age-associated diseases.

Ubiquitin-mediated proteostasis group

Latest News

Devinda passes her PhD viva!

Devinda passes her PhD viva!

Congratulations to Devinda Soegianto for passing her PhD viva with flying colours!

Check out Ubi-SCAPE (pre-print)

Check out Ubi-SCAPE (pre-print)

Check out Ubi-SCAPE! A tonne of hard work and thorough optimisations from (now former postdoc) Harvey went into getting the most out of the TUBE-based poly-ubiquitylomics workflow; don’t worry, we’ve kept the pre-print short…

Thanks to all co-authors, especially Matthias Trost & Andrew Frey, and the BBSRC Flexible Talent Mobility Award to The Babraham Institute and Newcastle University that allowed Harvey to go up to Newcastle for the final mass-spec experiments.

HSP90 SEC-MS paper is online!

HSP90 SEC-MS paper is online!

Just in time for the holidays! It really did take a village, this one—thanks to all co-authors, across three (/four?) continents, for making this possible.

Yasmeen & Stephen's book chapter on proteostasis dysregulation with ageing online now

Yasmeen & Stephen’s book chapter on proteostasis dysregulation with ageing online now

Our book chapter reviewing the literature on how the proteostasis network is re-wired during ageing is online today.

Funding

funding